Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies

Antibody functions such as neutralization require recognition of antigen by the Fab region, while effector functions are additionally mediated by interactions of the Fc region with soluble factors and cellular receptors. The efficacy of individual antibodies varies based on Fab domain characteristic...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Chu, Thach H., Crowley, Andrew R., Backes, Iara, Chang, Cheryl, Tay, Matthew, Broge, Thomas, Tuyishime, Marina, Ferrari, Guido, Seaman, Michael S., Richardson, Simone I., Tomaras, Georgia D., Alter, Galit, Leib, David, Ackerman, Margaret E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058349/
https://ncbi.nlm.nih.gov/pubmed/32092122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008083
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi