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Coming together at the hinges: Therapeutic prospects of IgG3

The human IgG3 subclass is conspicuously absent among the formats for approved monoclonal antibody therapies and Fc fusion protein biologics. Concern about the potential for rapid degradation, reduced plasma half-life, and increased immunogenicity due to marked variation in allotypes has apparently...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:MAbs
Egile Nagusiak: Chu, Thach H., Patz, Edward F., Ackerman, Margaret E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899677/
https://ncbi.nlm.nih.gov/pubmed/33602056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2021.1882028
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