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Integrating Hydrogen-Deuterium exchange mass spectrometry with Molecular Dynamics simulations to probe lipid-modulated conformational changes in membrane proteins
Biological membranes provide the medium through which membrane proteins move and function. It has become increasingly evident that direct interactions of membrane proteins with their surrounding lipids play key roles in regulating both protein conformations and function. However, the exact nature an...
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| Veröffentlicht in: | Nat Protoc |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7058097/ https://ncbi.nlm.nih.gov/pubmed/31605097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-019-0219-6 |
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