Mutation Profiles in Glioblastoma 3D Oncospheres Modulate Drug Efficacy

Glioblastoma (GBM) is a lethal brain cancer with a median survival time of approximately 15 months following treatment. Common in vitro GBM models for drug screening are adherent and do not recapitulate the features of human GBM in vivo. Here we report the genomic characterization of nine patient de...

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Publicado en:SLAS Technol
Main Authors: Wilson, Kelli M., Mathews-Griner, Lesley A., Williamson, Tara, Guha, Rajarshi, Chen, Lu, Shinn, Paul, McKnight, Crystal, Michael, Sam, Klumpp-Thomas, Carleen, Binder, Zev A., Ferrer, Marc, Gallia, Gary L., Thomas, Craig J., Riggins, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058093/
https://ncbi.nlm.nih.gov/pubmed/30289729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472630318803749
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