Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells

Glioblastoma multiforme (GBM) is a highly invasive and deadly brain tumor. Tumor cell invasion makes complete surgical resection impossible and reduces the efficacy of other therapies. Genome-wide analyses of mutations, copy-number changes, and expression patterns have provided new insights into gen...

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Autors principals: Weber, Genevieve L., Parat, Marie-Odile, Binder, Zev A., Gallia, Gary L., Riggins, Gregory J.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2011
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260001/
https://ncbi.nlm.nih.gov/pubmed/22064833
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