Family reunion via error correction: an efficient analysis of duplex sequencing data

BACKGROUND: Duplex sequencing is the most accurate approach for identification of sequence variants present at very low frequencies. Its power comes from pooling together multiple descendants of both strands of original DNA molecules, which allows distinguishing true nucleotide substitutions from PC...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Stoler, Nicholas, Arbeithuber, Barbara, Povysil, Gundula, Heinzl, Monika, Salazar, Renato, Makova, Kateryna D, Tiemann-Boege, Irene, Nekrutenko, Anton
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057607/
https://ncbi.nlm.nih.gov/pubmed/32131723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3419-8
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