Family reunion via error correction: an efficient analysis of duplex sequencing data

BACKGROUND: Duplex sequencing is the most accurate approach for identification of sequence variants present at very low frequencies. Its power comes from pooling together multiple descendants of both strands of original DNA molecules, which allows distinguishing true nucleotide substitutions from PC...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Bioinformatics
Main Authors: Stoler, Nicholas, Arbeithuber, Barbara, Povysil, Gundula, Heinzl, Monika, Salazar, Renato, Makova, Kateryna D, Tiemann-Boege, Irene, Nekrutenko, Anton
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Methodology Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057607/
https://ncbi.nlm.nih.gov/pubmed/32131723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3419-8
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