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Family reunion via error correction: an efficient analysis of duplex sequencing data

BACKGROUND: Duplex sequencing is the most accurate approach for identification of sequence variants present at very low frequencies. Its power comes from pooling together multiple descendants of both strands of original DNA molecules, which allows distinguishing true nucleotide substitutions from PC...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Main Authors: Stoler, Nicholas, Arbeithuber, Barbara, Povysil, Gundula, Heinzl, Monika, Salazar, Renato, Makova, Kateryna D, Tiemann-Boege, Irene, Nekrutenko, Anton
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057607/
https://ncbi.nlm.nih.gov/pubmed/32131723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3419-8
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