Cell-free chromatin particles released from dying host cells are global instigators of endotoxin sepsis in mice

We have earlier reported that cell-free chromatin (cfCh) particles that are released from dying cells, or those that circulate blood, can readily enter into healthy cells, illegitimately integrate into their genomes and induce dsDNA breaks, apoptosis and intense activation of inflammatory cytokines....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Mittra, Indraneel, Pal, Kavita, Pancholi, Namrata, Tidke, Pritishkumar, Siddiqui, Sophiya, Rane, Bhagyeshri, D’souza, Jenevieve, Shaikh, Alfina, Parab, Saili, Shinde, Sushma, Jadhav, Vishal, Shende, Soniya, Raghuram, Gorantla V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055819/
https://ncbi.nlm.nih.gov/pubmed/32130239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229017
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