Cell-free chromatin particles released from dying host cells are global instigators of endotoxin sepsis in mice

We have earlier reported that cell-free chromatin (cfCh) particles that are released from dying cells, or those that circulate blood, can readily enter into healthy cells, illegitimately integrate into their genomes and induce dsDNA breaks, apoptosis and intense activation of inflammatory cytokines....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mittra, Indraneel, Pal, Kavita, Pancholi, Namrata, Tidke, Pritishkumar, Siddiqui, Sophiya, Rane, Bhagyeshri, D’souza, Jenevieve, Shaikh, Alfina, Parab, Saili, Shinde, Sushma, Jadhav, Vishal, Shende, Soniya, Raghuram, Gorantla V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055819/
https://ncbi.nlm.nih.gov/pubmed/32130239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229017
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