Cell-free chromatin particles released from dying host cells are global instigators of endotoxin sepsis in mice

We have earlier reported that cell-free chromatin (cfCh) particles that are released from dying cells, or those that circulate blood, can readily enter into healthy cells, illegitimately integrate into their genomes and induce dsDNA breaks, apoptosis and intense activation of inflammatory cytokines....

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Mittra, Indraneel, Pal, Kavita, Pancholi, Namrata, Tidke, Pritishkumar, Siddiqui, Sophiya, Rane, Bhagyeshri, D’souza, Jenevieve, Shaikh, Alfina, Parab, Saili, Shinde, Sushma, Jadhav, Vishal, Shende, Soniya, Raghuram, Gorantla V.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055819/
https://ncbi.nlm.nih.gov/pubmed/32130239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229017
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