Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction

The immune system is designed to robustly respond to pathogenic stimuli but to be tolerant to endogenous ligands to not trigger autoimmunity. Here, we studied an endogenous damage-associated molecular pattern, mitochondrial DNA (mtDNA), during primary graft dysfunction (PGD) after lung transplantati...

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Detaylı Bibliyografya
Yayımlandı:Am J Respir Cell Mol Biol
Asıl Yazarlar: Mallavia, Beñat, Liu, Fengchun, Lefrançais, Emma, Cleary, Simon J., Kwaan, Nicholas, Tian, Jennifer J., Magnen, Mélia, Sayah, David M., Soong, Allison, Chen, Joy, Saggar, Rajan, Shino, Michael Y., Ross, David J., Derhovanessian, Ariss, Lynch, Joseph P., Ardehali, Abbas, Weigt, S. Sam, Belperio, John A., Hays, Steven R., Golden, Jeffrey A., Leard, Lorriana E., Shah, Rupal J., Kleinhenz, Mary Ellen, Venado, Aida, Kukreja, Jasleen, Singer, Jonathan P., Looney, Mark R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2020
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055700/
https://ncbi.nlm.nih.gov/pubmed/31647878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0140OC
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