Neutrophil Extracellular Traps Are Pathogenic in Primary Graft Dysfunction after Lung Transplantation

Rationale: Primary graft dysfunction (PGD) causes early mortality after lung transplantation and may contribute to late graft failure. No effective treatments exist. The pathogenesis of PGD is unclear, although both neutrophils and activated platelets have been implicated. We hypothesized that neutr...

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Veröffentlicht in:Am J Respir Crit Care Med
Hauptverfasser: Sayah, David M., Mallavia, Beñat, Liu, Fengchun, Ortiz-Muñoz, Guadalupe, Caudrillier, Axelle, DerHovanessian, Ariss, Ross, David J., Lynch III, Joseph P., Saggar, Rajan, Ardehali, Abbas, Ware, Lorraine B., Christie, Jason D., Belperio, John A., Looney, Mark R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351593/
https://ncbi.nlm.nih.gov/pubmed/25485813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201406-1086OC
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