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Identification of Potent Pyrazole Based APELIN Receptor (APJ) Agonists

The apelinergic system comprises the apelin receptor and its cognate apelin and elabela peptide ligands of various lengths. This system has become an increasingly attractive target for pulmonary and cardiometabolic diseases. Small molecule regulators of this receptor with good drug-like properties a...

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Bibliografische gegevens
Gepubliceerd in:Bioorg Med Chem
Hoofdauteurs: Narayanan, Sanju, Vasukuttan, Vineetha, Rajagopal, Sudarshan, Maitra, Rangan, Runyon, Scott P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055011/
https://ncbi.nlm.nih.gov/pubmed/31948845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.115237
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