Discovery of a Novel Small Molecule Agonist Scaffold for the APJ Receptor

The apelinergic system includes a series of endogenous peptides apelin, ELABELA/TODDLER and their 7-transmembrane G-protein coupled apelin receptor (APJ, AGTRL-1, APLNR). The APJ receptor is an attractive therapeutic target because of its involvement in cardiovascular diseases and potentially other...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Bioorg Med Chem
Päätekijät: Narayanan, Sanju, Maitra, Rangan, Deschamps, Jeffery R., Bortoff, Katherine, Thomas, James B., Zhang, Yanyan, Warner, Keith, Vasukuttan, Vineetha, Decker, Ann, Runyon, Scott P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955518/
https://ncbi.nlm.nih.gov/pubmed/27369451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.06.018
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia