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Nuclear Receptor 4A2 (NR4A2) Is a Druggable Target for Glioblastomas

INTRODUCTION: The orphan nuclear receptor 4A2 (NR4A2) has been extensively characterized in subcellular regions of the brain and is necessary for the function of dopaminergic neurons. The NR4A2 ligand, 1,1-bis (3(1)-indoly1)-1-(p-chlorophenyl)methane (DIM-C-pPhCl) inhibits markers of neuroinflammati...

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Karki, Keshav, Li, Xi, Jin, Un-Ho, Mohankumar, Kumaravel, Zarei, Mahsa, Michelhaugh, Sharon K., Mittal, Sandeep, Tjalkens, Ronald, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054911/
https://ncbi.nlm.nih.gov/pubmed/31754919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-019-03349-y
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