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The Combination of Patient Profiling and Preclinical Studies in a Mouse Model Based on NOD/Scid IL2Rγ (null) Mice Reconstituted With Peripheral Blood Mononuclear Cells From Patients With Ulcerative Colitis May Lead to Stratification of Patients for Treatment With Adalimumab

BACKGROUND: To date, responsiveness to tumor necrosis factor alpha inhibitors in ulcerative colitis (UC) patients is not predictable. This is partially due to a lack of understanding of the underlying inflammatory processes. The aim of this study was to identify immunological subgroups of patients w...

詳細記述

保存先:
書誌詳細
出版年:Inflamm Bowel Dis
主要な著者: Jodeleit, Henrika, Caesar, Janina, Villarroel Aguilera, Christina, Sterz, Sebastian, Holdt, Lesca, Beigel, Florian, Stallhofer, Johannes, Breiteneicher, Simone, Bartnik, Eckart, Siebeck, Matthias, Gropp, Roswitha
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054775/
https://ncbi.nlm.nih.gov/pubmed/31782956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izz284
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