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AAV Vector Immunogenicity in Humans: A Long Journey to Successful Gene Transfer
Gene therapy with adeno-associated virus (AAV) vectors has demonstrated safety and long-term efficacy in a number of trials across target organs, including eye, liver, skeletal muscle, and the central nervous system. Since the initial evidence that AAV vectors can elicit capsid T cell responses in h...
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| Veröffentlicht in: | Mol Ther |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Gene & Cell Therapy
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7054726/ https://ncbi.nlm.nih.gov/pubmed/31972133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.12.010 |
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