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Npl3 stabilizes R‐loops at telomeres to prevent accelerated replicative senescence
Telomere shortening rates must be regulated to prevent premature replicative senescence. TERRA R‐loops become stabilized at critically short telomeres to promote their elongation through homology‐directed repair (HDR), thereby counteracting senescence onset. Using a non‐bias proteomic approach to de...
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| 出版年: | EMBO Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7054685/ https://ncbi.nlm.nih.gov/pubmed/32026548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949087 |
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