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PD-L1 and MRN synergy in platinum-based chemoresistance of head and neck squamous cell carcinoma

BACKGROUND: We have been investigating the molecular mechanisms of cisplatin-induced chemoresistance in head and neck squamous cell carcinoma (HNSCC). Based on our previous findings, the present study investigates how the Mre11, Rad50, and NBS1 (MRN) DNA repair complex interacts at the molecular lev...

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Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Shen, Bin, Huang, Dongyan, Ramsey, Andrew J., Ig-Izevbekhai, Kevin, Zhang, Kevin, Lajud, Shayanne A., O’Malley, Bert W., Li, Daqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054324/
https://ncbi.nlm.nih.gov/pubmed/31853007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0697-x
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