PD-L1 and MRN synergy in platinum-based chemoresistance of head and neck squamous cell carcinoma

BACKGROUND: We have been investigating the molecular mechanisms of cisplatin-induced chemoresistance in head and neck squamous cell carcinoma (HNSCC). Based on our previous findings, the present study investigates how the Mre11, Rad50, and NBS1 (MRN) DNA repair complex interacts at the molecular lev...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Shen, Bin, Huang, Dongyan, Ramsey, Andrew J., Ig-Izevbekhai, Kevin, Zhang, Kevin, Lajud, Shayanne A., O’Malley, Bert W., Li, Daqing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054324/
https://ncbi.nlm.nih.gov/pubmed/31853007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0697-x
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