PD 098059, an inhibitor of ERK1 activation, attenuates the in vivo invasiveness of head and neck squamous cell carcinoma

Increased mortality of patients with oral cancer largely reflects the local and regional spread of the disease. The invasiveness of these tumours requires hydrolases which are regulated through AP-1-dependent transcriptional mechanisms. Since the amount/activity of transcription factors bound to the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Simon, C, Hicks, M J, Nemechek, A J, Mehta, R, Jr, B W O'Malley, Goepfert, H, Flaitz, C M, Boyd, D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 1999
Gaiak:
Regular Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363077/
https://ncbi.nlm.nih.gov/pubmed/10424744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690537
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