A Novel Chitosan-Hydrogel-Based Nanoparticle Delivery System for Local Inner Ear Application

HYPOTHESIS: A chitosan-hydrogel-based nanoparticle (nanohydrogel) delivery system can be used to deliver therapeutic biomaterials across the round window membrane (RWM) into the inner ear in a mouse model. BACKGROUND: Delivering therapies to the inner ear has always been a challenge for the Otolaryn...

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Bibliografiske detaljer
Udgivet i:Otol Neurotol
Main Authors: Lajud, Shayanne A., Nagda, Danish A., Qiao, Peter, Tanaka, Nobuaki, Civantos, Alyssa, Gu, Rende, Cheng, Zhiliang, Tsourkas, Andrew, O’Malley, Bert W., Li, Daqing
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365436/
https://ncbi.nlm.nih.gov/pubmed/25587675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0000000000000445
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