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A computational protocol for regulating protein binding reactions with a light sensitive protein dimer
Light-sensitive proteins can be used to perturb signaling networks in living cells and animals with high spatiotemporal resolution. We recently engineered a protein heterodimer that dissociates when irradiated with blue light and demonstrated that by fusing each half of the dimer to termini of a pro...
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| Опубликовано в: : | J Mol Biol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7054171/ https://ncbi.nlm.nih.gov/pubmed/31887287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.12.033 |
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