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Tuning the Binding Affinities and Reversion Kinetics of a Light Inducible Dimer Allows Control of Transmembrane Protein Localization
Inducible dimers are powerful tools for controlling biological processes through co-localizing signaling molecules. To be effective, an inducible system should have dissociation constants in the “off” and “on” state that bracket the concentrations of the molecules that are being controlled. Here, we...
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| Publié dans: | Biochemistry |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5332220/ https://ncbi.nlm.nih.gov/pubmed/27529180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00529 |
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