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Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins

The discovery of light-inducible protein–protein interactions has allowed for the spatial and temporal control of a variety of biological processes. To be effective, a photodimerizer should have several characteristics: it should show a large change in binding affinity upon light stimulation, it sho...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Main Authors: Guntas, Gurkan, Hallett, Ryan A., Zimmerman, Seth P., Williams, Tishan, Yumerefendi, Hayretin, Bear, James E., Kuhlman, Brian
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291625/
https://ncbi.nlm.nih.gov/pubmed/25535392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417910112
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