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Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins
The discovery of light-inducible protein–protein interactions has allowed for the spatial and temporal control of a variety of biological processes. To be effective, a photodimerizer should have several characteristics: it should show a large change in binding affinity upon light stimulation, it sho...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291625/ https://ncbi.nlm.nih.gov/pubmed/25535392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417910112 |
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