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Lung eosinophils increase vagus nerve-mediated airway reflex bronchoconstriction in mice
Eosinophils mediate airway hyperresponsiveness by increasing vagally mediated reflex bronchoconstriction. Here, we tested whether circulating or airway eosinophils change nerve function. Airway resistance in response to aerosolized 5-hydroxytryptamine (5-HT, 10–300 mM) was measured in wild-type mice...
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| Publié dans: | Am J Physiol Lung Cell Mol Physiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7052679/ https://ncbi.nlm.nih.gov/pubmed/31746625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00040.2019 |
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