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Lung eosinophils increase vagus nerve-mediated airway reflex bronchoconstriction in mice

Eosinophils mediate airway hyperresponsiveness by increasing vagally mediated reflex bronchoconstriction. Here, we tested whether circulating or airway eosinophils change nerve function. Airway resistance in response to aerosolized 5-hydroxytryptamine (5-HT, 10–300 mM) was measured in wild-type mice...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Nie, Zhenying, Maung, Jessica N., Jacoby, David B., Fryer, Allison D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052679/
https://ncbi.nlm.nih.gov/pubmed/31746625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00040.2019
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