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Eosinophils increase airway sensory nerve density in mice and in human asthma

In asthma, airway nerve dysfunction leads to excessive bronchoconstriction and cough. It is well established that eosinophils alter nerve function and that airway eosinophilia is present in 50 to 60% of asthmatics. However, the effects of eosinophils on airway nerve structure have not been establish...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Drake, Matthew G., Scott, Gregory D., Blum, Emily D., Lebold, Katherine M., Nie, Zhenying, Lee, James J., Fryer, Allison D., Costello, Richard W., Jacoby, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592848/
https://ncbi.nlm.nih.gov/pubmed/30185653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aar8477
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