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IL-5 Exposure In Utero Increases Lung Nerve Density and Airway Reactivity in Adult Offspring

Asthma is characterized by airway hyperreactivity and inflammation. In the lungs, parasympathetic and sensory nerves control airway tone and induce bronchoconstriction. Dysregulation of these nerves results in airway hyperreactivity. Humans with eosinophilic asthma have significantly increased senso...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Lebold, Katie M., Drake, Matthew G., Hales-Beck, Lauren B., Fryer, Allison D., Jacoby, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7110978/
https://ncbi.nlm.nih.gov/pubmed/31821769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0214OC
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