Inhibition of ATP hydrolysis restores airway surface liquid production in cystic fibrosis airway epithelia

Airway surface dehydration is a pathological feature of cystic fibrosis (CF) lung disease. CF is caused by mutations in the CF transmembrane conductance regulator (CFTR), a cyclic AMP-regulated Cl(−) channel controlled in part by the adenosine A(2B) receptor. An alternative CFTR-independent mechanis...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Lung Cell Mol Physiol
Asıl Yazarlar: van Heusden, Catharina, Button, Brian, Anderson, Wayne H., Ceppe, Agathe, Morton, Lisa C., O’Neal, Wanda K., Dang, Hong, Alexis, Neil E., Donaldson, Scott, Stephan, Holger, Boucher, Richard C., Lazarowski, Eduardo R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052677/
https://ncbi.nlm.nih.gov/pubmed/31800264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00449.2019
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