Mathematical Model of Nucleotide Regulation on Airway Epithelia: IMPLICATIONS FOR AIRWAY HOMEOSTASIS

In the airways, adenine nucleotides support a complex signaling network mediating host defenses. Released by the epithelium into the airway surface liquid (ASL) layer, they regulate mucus clearance through P2 (ATP) receptors, and following surface metabolism through P1 (adenosine; Ado) receptors. Th...

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Bibliographic Details
Main Authors: Zuo, Peiying, Picher, Maryse, Okada, Seiko F., Lazarowski, Eduardo R., Button, Brian, Boucher, Richard C., Elston, Timothy C.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Biomolecular Networks
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546543/
https://ncbi.nlm.nih.gov/pubmed/18662982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801516200
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