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Mathematical Model of Nucleotide Regulation on Airway Epithelia: IMPLICATIONS FOR AIRWAY HOMEOSTASIS

In the airways, adenine nucleotides support a complex signaling network mediating host defenses. Released by the epithelium into the airway surface liquid (ASL) layer, they regulate mucus clearance through P2 (ATP) receptors, and following surface metabolism through P1 (adenosine; Ado) receptors. Th...

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Detalles Bibliográficos
Main Authors: Zuo, Peiying, Picher, Maryse, Okada, Seiko F., Lazarowski, Eduardo R., Button, Brian, Boucher, Richard C., Elston, Timothy C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546543/
https://ncbi.nlm.nih.gov/pubmed/18662982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801516200
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