Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases

Glutathione is a major redox buffer, reaching millimolar concentrations within cells and high micromolar concentrations in airways. While glutathione has been traditionally known as an antioxidant defense mechanism that protects the lung tissue from oxidative stress, glutathione more recently has be...

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Udgivet i:Am J Physiol Cell Physiol
Main Authors: Chia, Shi B., Elko, Evan A., Aboushousha, Reem, Manuel, Allison M., van de Wetering, Cheryl, Druso, Joseph E., van der Velden, Jos, Seward, David J., Anathy, Vikas, Irvin, Charles G., Lam, Ying-Wai, van der Vliet, Albert, Janssen-Heininger, Yvonne M. W.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052607/
https://ncbi.nlm.nih.gov/pubmed/31693398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00410.2019
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