Dysregulation of the glutaredoxin/S-glutathionylation redox axis in lung diseases

Glutathione is a major redox buffer, reaching millimolar concentrations within cells and high micromolar concentrations in airways. While glutathione has been traditionally known as an antioxidant defense mechanism that protects the lung tissue from oxidative stress, glutathione more recently has be...

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Pubblicato in:Am J Physiol Cell Physiol
Autori principali: Chia, Shi B., Elko, Evan A., Aboushousha, Reem, Manuel, Allison M., van de Wetering, Cheryl, Druso, Joseph E., van der Velden, Jos, Seward, David J., Anathy, Vikas, Irvin, Charles G., Lam, Ying-Wai, van der Vliet, Albert, Janssen-Heininger, Yvonne M. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052607/
https://ncbi.nlm.nih.gov/pubmed/31693398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00410.2019
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