Mice lacking uterine enhancer of zeste homolog 2 have transcriptomic changes associated with uterine epithelial proliferation

Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that suppresses gene expression. Previously, we developed a conditional null model where EZH2 is knocked out in uterus. Deletion of uterine EZH2 increased proliferation of luminal and glandular epithelial cells. Herein, we used RNA-Se...

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Detalhes bibliográficos
Publicado no:Physiol Genomics
Main Authors: Mesa, Ana M., Mao, Jiude, Nanjappa, Manjunatha K., Medrano, Theresa I., Tevosian, Sergei, Yu, Fahong, Kinkade, Jessica, Lyu, Zhen, Liu, Yang, Joshi, Trupti, Wang, Duolin, Rosenfeld, Cheryl S., Cooke, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052568/
https://ncbi.nlm.nih.gov/pubmed/31841397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00098.2019
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