Mice lacking uterine enhancer of zeste homolog 2 have transcriptomic changes associated with uterine epithelial proliferation

Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that suppresses gene expression. Previously, we developed a conditional null model where EZH2 is knocked out in uterus. Deletion of uterine EZH2 increased proliferation of luminal and glandular epithelial cells. Herein, we used RNA-Se...

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Publicat a:Physiol Genomics
Autors principals: Mesa, Ana M., Mao, Jiude, Nanjappa, Manjunatha K., Medrano, Theresa I., Tevosian, Sergei, Yu, Fahong, Kinkade, Jessica, Lyu, Zhen, Liu, Yang, Joshi, Trupti, Wang, Duolin, Rosenfeld, Cheryl S., Cooke, Paul S.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052568/
https://ncbi.nlm.nih.gov/pubmed/31841397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00098.2019
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