Mice lacking uterine enhancer of zeste homolog 2 have transcriptomic changes associated with uterine epithelial proliferation

Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that suppresses gene expression. Previously, we developed a conditional null model where EZH2 is knocked out in uterus. Deletion of uterine EZH2 increased proliferation of luminal and glandular epithelial cells. Herein, we used RNA-Se...

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Publicado en:Physiol Genomics
Autores principales: Mesa, Ana M., Mao, Jiude, Nanjappa, Manjunatha K., Medrano, Theresa I., Tevosian, Sergei, Yu, Fahong, Kinkade, Jessica, Lyu, Zhen, Liu, Yang, Joshi, Trupti, Wang, Duolin, Rosenfeld, Cheryl S., Cooke, Paul S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052568/
https://ncbi.nlm.nih.gov/pubmed/31841397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00098.2019
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