Mice lacking uterine enhancer of zeste homolog 2 have transcriptomic changes associated with uterine epithelial proliferation

Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that suppresses gene expression. Previously, we developed a conditional null model where EZH2 is knocked out in uterus. Deletion of uterine EZH2 increased proliferation of luminal and glandular epithelial cells. Herein, we used RNA-Se...

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Bibliografiske detaljer
Udgivet i:Physiol Genomics
Main Authors: Mesa, Ana M., Mao, Jiude, Nanjappa, Manjunatha K., Medrano, Theresa I., Tevosian, Sergei, Yu, Fahong, Kinkade, Jessica, Lyu, Zhen, Liu, Yang, Joshi, Trupti, Wang, Duolin, Rosenfeld, Cheryl S., Cooke, Paul S.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052568/
https://ncbi.nlm.nih.gov/pubmed/31841397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00098.2019
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