TCR–pMHC bond conformation controls TCR ligand discrimination

A major unanswered question is how a TCR discriminates between foreign and self-peptides presented on the APC surface. Here, we used in situ fluorescence resonance energy transfer (FRET) to measure the distances of single TCR–pMHC bonds and the conformations of individual TCR–CD3ζ receptors at the m...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Mol Immunol
Main Authors: Sasmal, Dibyendu K., Feng, Wei, Roy, Sobhan, Leung, Peter, He, Yanran, Cai, Chufan, Cao, Guoshuai, Lian, Huada, Qin, Jian, Hui, Enfu, Schreiber, Hans, Adams, Erin J., Huang, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052167/
https://ncbi.nlm.nih.gov/pubmed/31530899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0273-6
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker