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Addiction associated N40D mu-opioid receptor variant modulates synaptic function in human neurons
The OPRM1 A118G single nucleotide polymorphism (SNP rs1799971) gene variant encoding the N40D ¼-opioid receptor (MOR) has been associated with dependence on opiates and other drugs of abuse but its mechanism is unknown. The frequency of G-allele carriers is ~40% in Asians, ~16% in Europeans, and ~3%...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Psychiatry |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7051890/ https://ncbi.nlm.nih.gov/pubmed/31481756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-019-0507-0 |
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