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Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells

BACKGROUND: Alcohol abuse produces an enormous impact on health, society, and the economy. Currently, there are very limited therapies available, largely due to the poor understanding of mechanisms underlying alcohol use disorders (AUDs) in humans. Oxidative damage of mitochondria and cellular prote...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Brain
Hauptverfasser: De Filippis, Lidia, Halikere, Apoorva, McGowan, Heather, Moore, Jennifer C., Tischfield, Jay A., Hart, Ronald P., Pang, Zhiping P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862119/
https://ncbi.nlm.nih.gov/pubmed/27160314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0221-7
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