Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells

BACKGROUND: Alcohol abuse produces an enormous impact on health, society, and the economy. Currently, there are very limited therapies available, largely due to the poor understanding of mechanisms underlying alcohol use disorders (AUDs) in humans. Oxidative damage of mitochondria and cellular prote...

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Bibliografische gegevens
Gepubliceerd in:Mol Brain
Hoofdauteurs: De Filippis, Lidia, Halikere, Apoorva, McGowan, Heather, Moore, Jennifer C., Tischfield, Jay A., Hart, Ronald P., Pang, Zhiping P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862119/
https://ncbi.nlm.nih.gov/pubmed/27160314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0221-7
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