Ethanol-mediated activation of the NLRP3 inflammasome in iPS cells and iPS cells-derived neural progenitor cells

BACKGROUND: Alcohol abuse produces an enormous impact on health, society, and the economy. Currently, there are very limited therapies available, largely due to the poor understanding of mechanisms underlying alcohol use disorders (AUDs) in humans. Oxidative damage of mitochondria and cellular prote...

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Detalles Bibliográficos
Publicado en:Mol Brain
Main Authors: De Filippis, Lidia, Halikere, Apoorva, McGowan, Heather, Moore, Jennifer C., Tischfield, Jay A., Hart, Ronald P., Pang, Zhiping P.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862119/
https://ncbi.nlm.nih.gov/pubmed/27160314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0221-7
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