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Coevolution analysis of amino-acids reveals diversified drug-resistance solutions in viral sequences: a case study of hepatitis B virus

The study of mutational landscapes of viral proteins is fundamental for the understanding of the mechanisms of cross-resistance to drugs and the design of effective therapeutic strategies based on several drugs. Antiviral therapy with nucleos(t)ide analogues targeting the hepatitis B virus (HBV) pol...

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Библиографические подробности
Опубликовано в: :Virus Evol
Главные авторы: Teppa, Elin, Nadalin, Francesca, Combet, Christophe, Zea, Diego Javier, David, Laurent, Carbone, Alessandra
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050494/
https://ncbi.nlm.nih.gov/pubmed/32158552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/veaa006
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