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Protein–protein interactions leave evolutionary footprints: High molecular coevolution at the core of interfaces

Protein–protein interactions are essential to all aspects of life. Specific interactions result from evolutionary pressure at the interacting interfaces of partner proteins. However, evolutionary pressure is not homogeneous within the interface: for instance, each residue does not contribute equally...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Teppa, Elin, Zea, Diego Javier, Marino‐Buslje, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699499/
https://ncbi.nlm.nih.gov/pubmed/28980349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3318
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