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Disentangling evolutionary signals: conservation, specificity determining positions and coevolution. Implication for catalytic residue prediction
BACKGROUND: A large panel of methods exists that aim to identify residues with critical impact on protein function based on evolutionary signals, sequence and structure information. However, it is not clear to what extent these different methods overlap, and if any of the methods have higher predict...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3515339/ https://ncbi.nlm.nih.gov/pubmed/22978315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-235 |
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