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Protein–protein interactions leave evolutionary footprints: High molecular coevolution at the core of interfaces

Protein–protein interactions are essential to all aspects of life. Specific interactions result from evolutionary pressure at the interacting interfaces of partner proteins. However, evolutionary pressure is not homogeneous within the interface: for instance, each residue does not contribute equally...

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Библиографические подробности
Опубликовано в: :Protein Sci
Главные авторы: Teppa, Elin, Zea, Diego Javier, Marino‐Buslje, Cristina
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699499/
https://ncbi.nlm.nih.gov/pubmed/28980349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3318
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