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Targeting viperin to the mitochondrion inhibits the thiolase activity of the trifunctional enzyme complex
Understanding the mechanisms by which viruses evade host cell immune defenses is important for developing improved antiviral therapies. In an unusual twist, human cytomegalovirus co-opts the antiviral radical SAM enzyme viperin (virus-inhibitory protein, endoplasmic reticulum–associated, interferon-...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7049979/ https://ncbi.nlm.nih.gov/pubmed/31980458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011526 |
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