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The antiviral enzyme viperin inhibits cholesterol biosynthesis
Many enveloped viruses bud from cholesterol-rich lipid rafts on the cell membrane. Depleting cellular cholesterol impedes this process and results in viral particles with reduced viability. Viperin (Virus Inhibitory Protein, Endoplasmic Reticulum-associated, Interferon iNducible) is an endoplasmic r...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8254119/ https://ncbi.nlm.nih.gov/pubmed/34029588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100824 |
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