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Viperin: An ancient radical SAM enzyme finds its place in modern cellular metabolism and innate immunity

Viperin plays an important and multifaceted role in the innate immune response to viral infection. Viperin is also notable as one of very few radical SAM–dependent enzymes present in higher animals; however, the enzyme appears broadly conserved across all kingdoms of life, which suggests that it rep...

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Pubblicato in:J Biol Chem
Autori principali: Ghosh, Soumi, Marsh, E. Neil G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450102/
https://ncbi.nlm.nih.gov/pubmed/32546482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV120.012784
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