Φορτώνει......
A novel peptide exerts potent immunosuppression by blocking the two-site interaction of NFAT with calcineurin
The calcineurin/nuclear factor of activated T cell (CN/NFAT) signaling pathway plays a critical role in the immune response. Therefore, inhibition of the CN/NFAT pathway is an important target for inflammatory disease. The conserved PXIXIT and LXVP motifs of CN substrates and targeting proteins have...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Biol Chem |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2020
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7049967/ https://ncbi.nlm.nih.gov/pubmed/31941790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010254 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|