Inhibition of Calcineurin/NFAT Signaling Blocks Oncogenic H-Ras Induced Autophagy in Primary Human Keratinocytes

Mutations of H-Ras, a member of the RAS family, are preferentially found in cutaneous squamous cell carcinomas (SCCs). H-Ras has been reported to induce autophagy, which plays an essential role in tissue homeostasis in multiple types of cancer cells and in fibroblasts, however, the potential role of...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Wang, Shuangshuang, Qian, Hua, Zhang, Liwei, Liu, Panpan, Zhuang, Dexuan, Zhang, Qun, Bai, Fuxiang, Wang, Zhihong, Yan, Yonggan, Guo, Jing, Huang, Jun, Wu, Xunwei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8328491/
https://ncbi.nlm.nih.gov/pubmed/34350189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.720111
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